In order to better prioritise adaptation decisions concerning impacts from a changing climate, there is a need for quantitative regional level assessments. In this policy update we provide insights from an impact assessment for three climate-related hazards (heat stress, river flood and forest fire) that is systematic and comparable across different countries in the European Union. The results show strongest increases in impacts for heat stress and forest fires. Hotspot regions are found in eastern and southern Europe due to their low adaptive capacity. The assessment of risk and capacities to adapt could be a basis to inform the allocation of financial resources in EU regional policy. Yet the reactions of policy makers are sceptic still.