Activities to extend the systems approach promoted by the OECD-IIASA Strategic Partnership and its Task Force are proposed. Issues the two organisations could collaborate on include sustainable and inclusive growth and well-being; linkages between finance, investment and climate change; concerted policies for the climate, ecosystems, energy, and water nexus; longer-term strategies for employment; managing the interactions between technological innovation and economic progress; a concerted approach to water, food, and trade; systems-based approaches for development co-operation to meet diverse needs and aspirations; strategies and governance to assess and manage systemic risk; improved methodology and tools for modelling; and adapting institutions to systems thinking to meet new challenges. Strengthening the systems approach within the OECD, and cooperation between the OECD, IIASA and outside partners are also discussed.