The Agriculture, Forestry and Other Land Use (AFOLU) sector encompasses managed ecosystems and offers significant mitigation opportunities while delivering food, wood and other renewable resources as well as biodiversity conservation, provided the sector adapts to climate change. Land-based mitigation measures represent some of the most important options currently available. They can both deliver carbon dioxide removal (CDR) and substitute for fossil fuels, thereby enabling emissions reductions in other sectors. The rapid deployment of AFOLU measures is essential in all pathways staying within the limits of the remaining budget for a 1.5°C target (high confidence). Where carefully and appropriately implemented, AFOLU mitigation measures are uniquely positioned to deliver substantial co-benefits and help address many of the wider challenges associated with land management. If AFOLU measures are deployed badly then, when taken together with the increasing need to produce sufficient food, feed, fuel and wood, they may exacerbate trade-offs with the conservation of habitats, adaptation, biodiversity and other services. At the same time the capacity of the land to support these functions may be threatened by climate change itself (high confidence).