The application of science, technology, and innovation (STI) solutions is crucial for increasing participation in climate change adaptation. This case study analyses Germany's best practices in utilizing STI to address climate change adaptation, including climate-resilient infrastructure development, climate information services, advanced modelling, public information campaigns, technology transfer, integration of climate change adaptation in regulations, research and development, urban climate modelling, and cross-cutting instruments. The internal validity of these best practices is assessed based on their effectiveness, reliability, and consistency, while the external validity considers their relevance and applicability in diverse contexts. By continuously evaluating their validity and sharing knowledge, countries and stakeholders can advance their climate change adaptation efforts for a more resilient and sustainable future.