ASA advances systems analysis as a meta-level approach to understand and govern complex socio-environmental systems. The overall objective is to increase realism, relevance, and agility of systems analysis. How? By harvesting new opportunities provided, in particular, by • New sources of data and methods to convert data into knowledge • Novel modelling approaches and underlying theories enabled by increased computational capabilities • Innovation through transfer of methods across disciplines and expansion of system boundaries • Continuous horizon scanning to identify novel matches between methodologies and applications across all thematic areas of IIASA • Enhanced transdisciplinary research