Super- and Coinfection: The Two Extremes

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http://eprints.org/relation/isVersionOf https://pure.iiasa.ac.at/id/document/4891 http://eprints.org/relation/isVolatileVersionOf https://pure.iiasa.ac.at/id/document/4891 http://eprints.org/relation/isCoversheetVersionOf https://pure.iiasa.ac.at/id/document/4891 archive 351 disk0/00/00/67/76 2016-01-15 02:14:57 2021-08-27 17:18:00 2016-01-15 02:14:57 monograph show 3 Nowak M.A. 7540 Sigmund K. 1050 Super- and Coinfection: The Two Extremes pub iis_ecl iis_mod prog_adn This paper investigates simplified models of multiple infection. Its first part deals with superinfection: the more virulent strain quickly outcompetes its rivals. The second part deals with coinfection: the rate of new infections produced by one strain is unaffected by the presence of other strains. The two cases differ in expectations for the resultant range of strains within the host population; they are similar in that both predict a considerable increase in virulence based on optimizing basic reproduction ratio of the pathogen do not work if several strains of pathogens compete within the host. 2002-02 published IR-02-008 IR-02-008 1481 282 public interim_report IIASA, Laxenburg, Austria 20 FALSE info:eu-repo/semantics/book