Do Large Dogs Die Young?

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http://eprints.org/relation/isVersionOf https://pure.iiasa.ac.at/id/document/13025 http://eprints.org/relation/isVolatileVersionOf https://pure.iiasa.ac.at/id/document/13025 http://eprints.org/relation/isCoversheetVersionOf https://pure.iiasa.ac.at/id/document/13025 archive 351 disk0/00/00/80/27 2016-01-15 08:38:54 2021-08-27 17:19:35 2016-01-15 08:38:54 monograph show 3 Galis F. Sluijs I. van der Van Dooren T.J.M. Metz J.A.J. 7506 Nussbaumer M. 1852 Do Large Dogs Die Young? pub iis_ecl prog_eep In most animal taxa, longevity increases with body size across species, as predicted by the oxidative stress theory of aging. In contrast, in within-species comparisons of mammals and especially domestic dogs (e.g. Patronek, 97; Michell, 99; Egenvall et al., 2000; Speakman et al, 2003) longevity decreases with body size. We explore two datasets for dogs and find support for a negative relationship between size and longevity if we consider variation across breeds. Within breeds, however, the relationship is not negative. The negative across-breed relationship is probably the consequence of short lifespans in large breeds. Artificial selection for extremely high growth rates in large breeds appears to have led to developmental diseases that seriously diminish longevity. 2006-12 published IR-06-072 IR-06-072 206 1485 public interim_report IIASA, Laxenburg, Austria 26 FALSE info:eu-repo/semantics/book