Satellite-based estimates of ambient air pollution and global variations in childhood asthma prevalence

9964 11 68035 2 188023 document 68035 Satellite-based estimates of ambient air pollution and global variations in childhood asthma prevalence.pdf application/pdf 0cf85a8900d7f992219b7f7f10924ab7 MD5 447112 2016-07-25 11:22:10 https://pure.iiasa.ac.at/id/eprint/9964/1/Satellite-based%20estimates%20of%20ambient%20air%20pollution%20and%20global%20variations%20in%20childhood%20asthma%20prevalence.pdf 9964 1 1 application/pdf text en public cc_by

Satellite-based estimates of ambient air pollution and global variations in childhood asthma prevalence.pdf

published 68037 2 188029 document 68037 lightbox.jpg image/png 667fe18cc01ec5fd2d8a04b05b837d14 MD5 84127 2016-07-25 11:32:26 https://pure.iiasa.ac.at/id/eprint/9964/2/lightbox.jpg 9964 2 2 image/png other Thumbnails conversion from text to thumbnail_lightbox en public

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http://eprints.org/relation/isVersionOf https://pure.iiasa.ac.at/id/document/68035 http://eprints.org/relation/isVolatileVersionOf https://pure.iiasa.ac.at/id/document/68035 http://eprints.org/relation/isIndexCodesVersionOf https://pure.iiasa.ac.at/id/document/68035 archive 351 disk0/00/00/99/64 2016-01-15 08:46:45 2021-08-27 17:22:30 2016-01-15 08:46:45 article show Anderson H.R. Butland B.K. van Donkelaar A. Brauer M. Strachan D.P. Clayton T. van Dingenen R. Amann M. 1136 0000-0002-1963-0972 Brunekreef B. Cohen A. Dentener F. Lai C. Lamsal L.N. Martin R.V. Satellite-based estimates of ambient air pollution and global variations in childhood asthma prevalence pub iis_env prog_air prog_mag BACKGROUND: The effect of ambient air pollution on global variations and trends in asthma prevalence is unclear. OBJECTIVES: To investigate community-level associations between asthma prevalence data from the International Study of Asthma and Allergies in Childhood (ISAAC) and satellite-based estimates of particulate matter with aerodynamic diameter <2.5 microns (PM2.5) and nitrogen dioxide (NO2), and modelled estimates of ozone. METHODS: We assigned satellite-based estimates of PM2.5 and NO2 at a spatial resolution of 0.1 x 0.1 and modelled estimates of ozone at a resolution of 1 x 1 to 183 ISAAC centres. We used centre-level prevalence of severe asthma as the outcome and multilevel models to adjust for gross national income (GNI) and centre- and country-level sex, climate and population density. We examined associations (adjusting for GNI) between air pollution and asthma prevalence over time in centres with data from ISAAC Phase One (mid-1900s) and Phase Three (2001-2003). RESULTS: For the 13-14 year age group (128 centres in 28 countries) the estimated average within-country change in centre-level asthma prevalence per 100 children per 10% increase in centre-level PM2.5 and NO2 was -0.043 (-0.139, 0.053) and 0.017 (-0.030, 0.064) respectively. For ozone the estimated change in prevalence per ppbV was -0.116 (-0.234, 0.001). Equivalent results for the 6-7 year age-group (83 centres in 20 countries) though slightly different were not significantly positive. For the 13-14 year age-group, change in centre-level asthma prevalence over time per 100 children per 10% increase in PM2.5 from Phase One to Phase Three was -0.139 (-0.347, 0.068). The corresponding association with ozone (per ppbV) was -0.171 (-0.275, -0.067). CONCLUSION: In contrast to reports from within-community studies of individuals exposed to traffic pollution we did not find evidence of a positive association between ambient air pollution and asthma prevalence as measured at the community level. 2012-09 published National Institute of Environmental Health Sciences 10.1289/ehp.1104724 XJ-12-079 Environmental Health Perspectives; 120(9):1333-1339 (September 2012) (Published online 1 May 2012) [doi:10.1289/ehp.1104724] 15 public Environmental Health Perspectives 120 9 1333-1339 TRUE 1552-9924 FALSE info:eu-repo/semantics/article